Name | N-(2-hydroxy-3-sulfopropyl)-*3,5-dimethoxyaniline |
Synonyms | HDAOS hdaos HDAOS SODIUM SALT N-(2-hydroxy-3-sulfopropyl)-*3,5-dimethoxyaniline N-(2-HYDROXY-3-SULFOPROPYL)-*3,5-DIMETHO XYANILINE S N-(2-hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline sodium N-(2-Hydroxy-3-sulfopropyl)-3,5-dimethoxyaniline sodium salt N-(2-HYDROXY-3-SULFOPROPYL)-3,5-DIMETHOXYANILINE SODIUM SALT HDAOS (N-(2-Hydroxy-3-sulfopropyl)- 3,5-dimethoxyaniline sodium HDAOS (N-(2-HYDROXY-3-SULFOPROPYL)- 3,5-DIMETHOXYANILINE SODIUM SALT |
CAS | 82692-88-4 |
InChI | InChI=1/C11H17NO6S.Na/c1-17-10-3-8(4-11(5-10)18-2)12-6-9(13)7-19(14,15)16;/h3-5,9,12-13H,6-7H2,1-2H3,(H,14,15,16);/q;+1 |
InChIKey | SVLRFMQGKVFRTB-UHFFFAOYSA-M |
Molecular Formula | C11H16NNaO6S |
Molar Mass | 313.3 |
Appearance | powder to crystal |
Color | White to Almost white |
Storage Condition | Sealed in dry,Room Temperature |
Sensitive | Sensitive to heat |
MDL | MFCD00063425 |
Use | The new Trinder "S reagent is a highly water-soluble aniline derivative, which is widely used in diagnostic testing and biochemical testing. It has several advantages over conventional chromogenic reagents in colorimetric determination of hydrogen peroxide activity. The new Trinder "S reagent is stable enough to be used in both solutions and test line detection systems. In the presence of hydrogen peroxide and peroxidase, the new Trinder "s reagent forms a very stable purple or blue dye during the oxidative coupling reaction with 4-aminoantipyrine (4-AA) or 3-methylbenzothiazole sulfone hydrazone (MBTH). The molar absorbance of the dye coupled with MBTH is 1.5-2 times higher than that of the dye coupled with 4-AA. However, 4-AA solution is more than MBTH solution |
Hazard Symbols | Xi - Irritant |
Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
biological activity | HDAOS is a novel Trinder's reagent, which is a highly water-soluble aniline derivative, it is widely used in diagnostic tests and biochemical tests. |
Use | the novel Trinder's reagent is a highly water-soluble aniline derivative, which is widely used in diagnostic tests and biochemical tests. There are several advantages over conventional chromogenic reagents in the Colorimetric Determination of hydrogen peroxide activity. The novel Trinder's reagent is sufficiently stable to be used in both solutions and in assay line detection systems. In the oxidative coupling reaction with 4-aminoantipyrine (4-AA) or 3-methylbenzothiazole sulfone hydrazone (MBTH) in the presence of hydrogen peroxide and peroxidase, A very stable violet or blue dye is formed. The molar absorbance with the MBTH coupling dye was 1.5-2 times higher than with the 4-AA coupling dye; However, the 4-AA solution was more stable than the MBTH solution. The substrate is enzymatically oxidized by its oxidase enzyme to produce hydrogen peroxide. The concentration of hydrogen peroxide corresponds to the substrate concentration. Thus, the amount of substrate can be determined by the color development of the peroxycoupling reaction. Glucose, alcohol, acyl-CoA and cholesterol can be used to detect those substrates coupled to the novel Trinder's reagent and 4-AA. There are 10 new Trinder's reagents. Among the novel Trinder's reagents, tours are the most commonly used. However, for specific substrates, it is necessary to test different kinds of novel Trinder's reagents for the development of an optimal detection system. |